Revised in March 2023, the research review addresses the current state-of-the-science of CTE, including an in-depth look at available peer-reviewed scientific literature and a bulleted quick-reference summary for clinicians and the operational community. The revised fact sheet is a quick reference for researchers, the operational community, and clinicians to understand what is known, and not known, about CTE.
In cases with confirmed CTE, there is noteworthy overlap of symptomology and comorbid neuropathological conditions. CTE currently cannot be diagnosed in living persons. The clinical syndrome for living persons, Traumatic Encephalopathy Syndrome, is associated with CTE but is not diagnostic of the condition.