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Hepatitis B

Hepatitis B Vaccine Resource Center

Hepatitis BHepatitis B is a liver infection caused by the hepatitis B virus (HBV). Hepatitis B is transmitted when blood, semen, or another body fluid from a person infected with the virus enters the body of someone who is not infected. This can happen through sexual contact; sharing needles, syringes, other injection equipment; or from mother to baby at birth.

For many, especially children, hepatitis B infection is asympomatic. For some people, including most infected in infancy, hepatitis B can become a long-term, chronic infection. Chronic hepatitis B can lead to serious health issues, like cirrhosis or liver cancer.

The first dose of hepatitis B vaccine is given at birth, with the three-dose series completed between 6 and 18 months of age. Older children and adolescents who did not previously receive the hepatitis B vaccine should be immunized.

Source: Centers for Disease Control and Prevention

Resource Center

You will find below all of the resources you will need about the hepatitis B vaccine. More will be added as they are published or released.

Information Paper Date
Hepatitis B Infection and Hepatitis B Vaccines Dec. 6, 2017

Counting Doses in Combined Regimens of Monovalent and Bivalent Hepatitis A and Hepatitis B vaccines

Aug. 30, 2019
Standing Orders Date
Hepatitis B Vaccine (Pediatric)
April 6, 2023
Hepatitis B Vaccine (Adult)
May 17, 2023
Vaccine Information Statements (VIS) Date
Hepatitis B Vaccine: What You Need to Know
May 12, 2023
Your Child's First Vaccines
Oct. 15, 2021
Manufacturer Package Inserts Date
Dec. 19, 2018
May 6, 2020
April 26, 2023
Nov. 30, 2021
Recombivax HB
Dec. 21, 2018
Dec. 18, 2018
April 12, 2023
Advisory Committee on Immunization Practices (ACIP) Recommendations Date
Hepatitis B Vaccine
April 20, 2018

You also may be interested in...

Counting Doses in Combined Regimens of Monovalent and Bivalent Hepatitis A and Hepatitis B vaccines

Fact Sheet

This information paper describes the required number of doses, using various combinations of monovalent (single antigen) hepatitis A and hepatitis B vaccines and the bivalent (combination hepatitis A and hepatitis B) vaccine, to ensure adequate immunity against both diseases.

Progress Toward Hepatitis B Control and Elimination of Mother-to-Child Transmission of Hepatitis B Virus — Western Pacific Region, 2005–2017


In 1990, chronic hepatitis B virus infection in the World Health Organization Western Pacific Region (WPR) was highly endemic. During 2005-2017, increases in coverage for both the hepatitis B vaccine birth dose and third dose led to a decline in prevalence of chronic hepatitis infection in children to <1% in 25 countries.

Hepatitis B


Hepatitis B degrades the health and military operational capabilities of those affected and demands significant health care resources for its clinical management.

Community-Based Services to Improve Testing and Linkage to Care Among Non–U.S.-Born Persons with Chronic Hepatitis B Virus Infection — Three U.S. Programs, October 2014–September 2017


The CDC funded three programs to develop hepatitis B testing and linkage-to-care programs serving non–U.S.-born persons during 2014–2017; 78% of persons with chronic HBV infection were linked to care using community-based services.

Recommendations of the Advisory Committee on Immunization Practices for Use of a Hepatitis B Vaccine with a Novel Adjuvant


In November 2017, a single-antigen Hepatitis B vaccine with a novel immunostimulatory sequence adjuvant was approved by the Food and Drug The Advisory Committee on Immunization Practices (ACIP) has recommended this vaccine for use in persons aged ≥18 years.

Hepatitis B ACIP Guidelines


Notes from the Field: False-Negative Hepatitis B Surface Antigen Test Results in a Hemodialysis Patient — Nebraska, 2017


In March 2017, a hemodialysis clinic reported a patient who had tested negative for hepatitis B virus (HBV) surface antigen (HBsAg) after vaccination in 2010 and who later tested positive for HBsAg. A public health investigation subsequently determined that the false-negative results were caused by a surface antigen mutation.

Notes from the Field: Increase in Acute Hepatitis B Infections — Pasco County, Florida, 2011–2016


An increase in acute hepatitis B virus infections in Florida led to targeted outreach for testing and vaccination programs for persons at high risk, and resulted in the administration of more than 300 doses of hepatitis B vaccine.

Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices


This report updates and summarizes previously published recommendations from the Advisory Committee on Immunization Practices (ACIP) and CDC regarding the prevention of Hepatitis B virus infection in the United States.

Hepatitis B Infection and Hepatitis B Vaccines

Fact Sheet

This information paper describes hepatitis B virus and the vaccines to prevent it.

Immunization Recommendations for Disaster Response Operations

Fact Sheet

This information paper provides immunization recommendations and resources for Department of Defense (DOD) personnel supporting disaster response operations, both in CONUS and OCONUS.

ASIP Dosing Schedule for MMR and Hepatitis A and B

Fact Sheet

This fact sheet provides the dosing schedule for MMR, Varicella, Hepatitis A and Hepatitis B vaccines.

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Last Updated: May 23, 2023
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