Skip to main content

Military Health System

Smallpox (ACAM2000)

DoD Smallpox Vaccination Program Resource Center

Smallpox Disease and Smallpox Vaccine information paper (includes updated guidance on avoiding contamination while drawing vaccine from the vial)

Questions and Answers about Smallpox and Smallpox Vaccine

SmallpoxSmallpox disease had a mortality rate of approximately 30 percent, and because of a successful vaccination program it was declared globally eradicated in 1980. Naturally occurring smallpox was highly contagious, and was transmitted from an infected person to a susceptible (unvaccinated) person by close contact with respiratory secretions and/or infected skin. When smallpox disease was circulating, the only known reservoir for the virus was humans.

Once infected, a person usually has no symptoms and is not contagious during the incubation period, which ranges from 7-17 days.  Symptoms then begin with high fever, headache, body aches and fatigue. This may last 2-4 days, and then the rash develops. The rash first appears on the oral mucosa, face, and forearms, then spreads to the trunk and legs. A person is most infectious during the first week of the rash and is no longer infectious after all scabs have separated, usually 3-4 weeks after onset.

There is currently one smallpox vaccine licensed in the United States, ACAM2000, and is given in a pre-event setting only to select, designated groups including certain members of the U.S. military. The smallpox vaccine is administered in a single dose by the percutaneous route (scarification) using 15 jabs with a stainless steel bifurcated needle that has been dipped into the reconstituted vaccine. A few days following successful administration of the vaccine, a lesion forms at the vaccination site. This lesion contains vaccinia virus capable of infecting other parts of your body or infecting others who come in contact with the vaccination site directly or anything that contains drainage from the lesion.  For this reason, all smallpox vaccinees are taught, and must practice, proper vaccination site and dressing care. 

Source: Centers for Disease Control and Prevention

You also may be interested in...

ALMAJCOM SMALLPOX VACCINATIONS FOR AIR FORCE FEDERAL CIVILIAN EMPLOYEES

Policy

ALCOAST SMALLPOX VACCINATION PROGRAM UPDATE

Policy

ALCOAST SMALLPOX VACCINATION PROGRAM (SVP) UPDATE

MARADMIN Civilian AUTHORIZATION TO BEGIN SMALLPOX VACCINATION PROGRAM

Policy

MARADMIN (Civilian) AUTHORIZATION TO BEGIN SMALLPOX VACCINATION PROGRAM

Air Force Smallpox Vaccine Implementation Plan

Policy

Anthrax and Smallpox Vaccination of Department of Defense Personnel and Dependents

Policy

ALCOAST SMALLPOX VACCINATION PROGRAM MEDICAL GUIDANCE

Policy

ALCOAST SMALLPOX VACCINATION PROGRAM (SVP) MEDICAL GUIDANCE

ALCOAST SMALLPOX VACCINATION PROGRAM

Policy

ALCOAST SMALLPOX VACCINATION PROGRAM (SVP)

Army SPV Implementation Plan

Policy

NAVADMIN SMALLPOX VACCINATION PROGRAM IMPLEMENTATION GUIDANCE

Policy

NAVADMIN SMALLPOX VACCINATION PROGRAM (SVP) IMPLEMENTATION GUIDANCE

GENADMIN SMALLPOX VACCINATION PROGRAM FOR MILITARY TREATMENT FACILITIES

Policy

GENADMIN SUBJ/SMALLPOX VACCINATION PROGRAM (SVP) FOR MILITARY TREATMENT FACILITIES

MARADMIN AUTHORIZATION TO BEGIN SMALLPOX VACCINATION PROGRAM

Policy

MARADMIN AUTHORIZATION TO BEGIN SMALLPOX VACCINATION PROGRAM (SVP)

Air Force Implementation of the Smallpox Vaccination Program

Policy

Approval of Marine Corps Smallpox Implementation Plan

Policy

Approval of Coast Guard Smallpox Implementation Plan

Policy

Approval of Navy Smallpox Implementation Plan

Policy
<< < 1 2 3 4 5 > >> 
Showing results 46 - 60 Page 4 of 5
Last Updated: January 21, 2020
Follow us on Instagram Follow us on LinkedIn Follow us on Facebook Follow us on Twitter Follow us on YouTube Sign up on GovDelivery