Skip main navigation

Military Health System

Clear Your Browser Cache

This website has recently undergone changes. Users finding unexpected concerns may care to clear their browser's cache to ensure a seamless experience.

Corneal Collagen Cross Linking in the Military a Game Changer

Image of Corneal collagen cross-linking, known as CXL, the first and only treatment to date that is proven to stop Keratoconus, KCN, progression. Corneal collagen cross-linking, known as CXL, the first and only treatment to date that is proven to stop Keratoconus, KCN, progression.

For years, Keratoconus has been a disqualifying condition in the military, and a reason why refractive surgery is often denied to service members.

Keratoconus (pronounced Keh·ruh·tow·kow·nuhs), or KCN, is an eye condition where the front part of the eye (cornea) gradually thins out and bulges causing irregularity and blurred vision.

KCN may result from eye rubbing. It has also been linked to sleep apnea, asthma, allergy, eczema, vernal conjunctivitis, floppy eyelid syndrome, connective tissue disorders, or a family history of KCN. Historically, the primary treatment for KCN was contact lenses when eyeglasses were not sufficient to correct the irregular astigmatism. Severe cases were treated with corneal transplantation.

Navy Capt. (Dr.) John Cason, prior ophthalmology specialty leader and refractive surgery advisor, stated that, he reviewed about 2 to 5 sailor applicants per month for possible waiver for accession into the military due to KCN.

In 2016, the Food and Drug Administration approved corneal collagen cross-linking, known as CXL. This is the first and only treatment proven to stop KCN progression.

Air Force Col. (Dr.) Matthew Caldwell, ophthalmology consultant to the Air Force Surgeon General, called CXL a "readiness game changer." He noted that "KCN is of special interest to the military as the age range of impact nearly exactly overlaps years of active-duty service." The onset can happen before or after acceptance into the military when screening is too late.

"KCN impacts the ability to deploy and can degrade vision excluding careers in aviation, Special Forces, and in severe cases, even less visually intensive administrative work," added Caldwell.

Since the FDA approval, hundreds of service members have been treated with CXL. And a majority of these have been able to retain their military careers.

Air Force Col. (Dr.) Joseph Giovannini, cornea specialist at the David-Grant USAF Medical Center at Travis Air Force Base in California stated, "I have seen several military careers saved by the procedure."

Air Force Capt. Lowell DePalma, an aviator who had bilateral CXL, backed up Giovannini, "CXL has allowed me to keep my job and helped my future eye exams to be more predictable."

Currently, ophthalmology consultants are able to recommend acceptance waivers for military candidates with early KCN as long as they are able to show stability after CXL procedure.

"CXL has offered the possibility of military service for a group of candidates with mild symptoms from KCN," stated Cason. In the past, these volunteers didn't have the option of continued service due to restrictive guidelines that did not offer any flexibility with treatment. CXL has given these people the possibility of treatment, stability, and a future military service that were previously denied."

In the future, CXL may also significantly expand the options of vision-enhancing refractive surgery. In the past, service members with abnormal corneal scans were disqualified from refractive surgery. However, over the past decade, CXL plus refractive surgery outcomes have been favorable.

"The advent of CXL has helped tremendously to retain highly trained individuals and increase the applicant pool for the armed services," explained Air Force Lt. Col. (Dr.) James Townley, refractive surgery consultant to the Surgeon General of the Air Force.

As technology continues to advance, the use of CXL and refractive surgery will help more service members remain on active duty.

All authored materials constitute the personal statements of the names listed above and are not intended to constitute an endorsement by the Unites States Air Force or any other Federal Government entity

You also may be interested in...

Report
Jan 1, 1997

MSMR Vol. 3 No. 4 – June 1997

.PDF | 132.99 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Risk factor analysis (part I), hospitalizations, OJE; Selected sentinel reportable diseases, May 1997; Selected sentinel reportable diseases, 2 year trends; Reportable sexually transmitted diseases, May 1997; ...

Report
Jan 1, 1997

MSMR Vol. 3 No. 6 – September 1997

.PDF | 197.28 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Hyponatremia secondary to overhydration; Selected sentinel reportable diseases, August 1997; Selected sentinel reportable diseases, 2 year trends; Reportable sexually transmitted diseases, August 1997; ...

Report
Jan 1, 1997

MSMR Vol. 3 No. 5 – July/August 1997

.PDF | 165.88 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Plasmodium vivax malaria of Korean origin, 1997; Selected sentinel reportable diseases, June 1997; Selected sentinel reportable diseases, 2 year trends; Reportable sexually transmitted diseases, June 1997; ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 4 – April 1996

.PDF | 125.97 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Rash outbreaks, U.S. forces operating in Belgium; Selected notifiable conditions; Notifiable sexually transmitted diseases; Injuries and fitness in BCT units, FLW, MO; Surveillance trends: Hospitalization rates ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 10 – December 1996

.PDF | 414.30 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Overview of military respiratory disease surveillance; Selected notifiable conditions; Notifiable sexually transmitted diseases; ARD surveillance among Army basic trainees; Air Force Influenza Surveillance ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 3 – March 1996

.PDF | 279.20 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Cutaneous Leishmaniasis, WRAMC; Selected notifiable conditions; Notifiable sexually transmitted diseases; Preliminary data: HEARS; Leprosy in a Navy family member, Ft Hood; Surveillance Trends: Hospitalization ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 9 – November 1996

.PDF | 106.69 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Shigella sonnei diarrheal outbreaks; Selected notifiable conditions; Notifiable sexually transmitted diseases; TB Skin Test Converters, Ft. Leavenworth; Surveillance trends: Hospitalization rates, Bosnia; ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 7 – September 1996

.PDF | 107.12 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Rash illness outbreak among British Soldiers; Selected notifiable conditions; Notifiable sexually transmitted diseases; Leptospirosis - Tripler Army Medical Center; Surveillance trends: Hospitalization rates, ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 6 – July 1996

.PDF | 150.06 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Hookworm Disease - Ft. Drum, NY; Selected notifiable conditions; Notifiable sexually transmitted diseases; Malaria Outbreak, Vincenza, Italy; Surveillance trends: Hospitalization rates, Bosnia; Bosnia update: ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 1 – January 1996

.PDF | 134.17 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Cold Weather Injuries, Oct - Dec, 1995; Selected notifiable conditions; Notifiable sexually transmitted diseases; Multidrug-Resistant Tuberculosis – WRAMC; Surveillance Trends: CWI hospitalization rates; ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 8 – October 1996

.PDF | 158.75 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Vivax malaria in U.S. forces – Korea; Selected notifiable conditions; Notifiable sexually transmitted diseases; Diarrhea outbreak – Croatia; 1996-97 Influenza immunization guidelines; ARD surveillance update; ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 2 – February 1996

.PDF | 103.48 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Injuries in integrated BCT units, FLW, MO; Selected notifiable conditions; Notifiable sexually transmitted diseases; Cold weather injuries, Ft. Drum, NY; Surveillance Trends: Hospitalizations, Bosnia; Bosnia ...

Report
Jan 1, 1996

MSMR Vol. 2 No. 5 – May 1996

.PDF | 116.35 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Listeria monocytogenes meningitis, Ft. Bragg; Selected notifiable conditions; Notifiable sexually transmitted diseases; Strongyloides stercoralis hyperinfection; Surveillance trends: Hospitalization rates, ...

Report
Jan 1, 1995

MSMR Vol. 1 No. 5 – August 1995

.PDF | 100.59 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Heat related Injuries, July 1995; Selected notifiable conditions; Notifiable sexually transmitted diseases; Heat / Cold weather injuries, Jan - Jul, 1995; Classification and disposition of heat injuries; ...

Report
Jan 1, 1995

MSMR Vol. 1 No. 9 – December 1995

.PDF | 111.88 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Hydrogen sulfide exposure, Ft Irwin; Selected notifiable conditions; Notifiable sexually transmitted diseases; GBS following Influenza immunization; Korean hemorrhagic fever, Korea; Escherichia coli 0157:H7, ...

Skip subpage navigation
Refine your search
Last Updated: July 11, 2023
Follow us on Instagram Follow us on LinkedIn Follow us on Facebook Follow us on X Follow us on YouTube Sign up on GovDelivery