Prior history of TBI may predispose an individual to increased risk of subsequent TBI, which may result from less force, and lengthier recovery from post-injury symptoms. Activities such as contact sports and military service carry particular risk for multiple TBI.

This new supplemental product to the detailed research review is designed to provide a brief summary of actionable clinical pearls for consideration during the evaluation and treatment of service members who have sustained multiple concussions.

Publication of the Defense Intrepid Network for TBI and Brain Health.

This research review provides an overview of the state of the science regarding comorbid traumatic brain injury and suicide, as well as suicide attempts, with a focus on military personnel.

This clinical recommendation, newly revised in 2024, includes specific recommendations of both pharmacologic and non-pharmacologic treatment of the most common types of post-traumatic headache, two additional PTH subtypes, and expanded information on medication overuse headache.

This clinical recommendation is an evidence-based return to activity protocol for primary care managers and concussion/traumatic brain injury clinic providers. The PRA is a six-step approach that begins after the provider performs the MACE 2 (Military Acute Concussion Evaluation 2) and the patient is diagnosed with a concussion, also known as a mild TBI.

This TBICoE clinical recommendation allows primary care managers to make an informed, evidenced-based decision regarding whether or not imaging is indicated following a concussion/mild TBI.

The clinical pearls are a concise one-page document that serves as a quick reference for military clinicians treating service members with a mild TBI who may present with suicidal ideation.

This document provides guidance for the Department of Defense medical and operational research and development activities to coordinate, optimize, and advance warfighter brain health science.